Vaccine agents can be either Live whole cell ones, Killed whole cell or sub-unit vaccines. Sub Units can be one specific protein ( Spike protein ) or a slice of DNA or mRNA. Sub unit vaccines are developed only after molecular biology techniques are developed. Between live vaccine and killed vaccine, which is developed earlierContinue reading “Vaccine Story-1”
Category Archives: Ideas of health
The Koch-Pasteur Rivalry
Robert Koch is credited with the discovery of the Koch’s Postulate. Then he went on to discover the Anthrax bacillus, Vibrio Cholera and of course the Mycobacterium Tuberculosis. It should be taken as the greatest medical achievement of all time. He was awarded the 1905 Nobel prize for his seminal work. What is so greatContinue reading “The Koch-Pasteur Rivalry”
Vaccine Efficacy vs Immunological Memory
We have developed Covid vaccines that are highly efficacious ( 94%) as early as December 2020. Yet in the mid 2021, the world reeled under the attack of Delta and the Omicrons. Today we are going to discuss two aspect of the Covid Vaccines: Vaccine Efficacy (VE) Immunological Memory ( IM) Let us classify allContinue reading “Vaccine Efficacy vs Immunological Memory”
Correlates of Protection
In search of a true Correlate of protection against new viruses. The old world of immunology and vaccination are crumbling. For 100 years we thought that our antibody levels are synonymous with Protection against the microbe. Whenever the efficacy of a vaccine needed evaluation, we only measured the serum antibody level against the antigen atContinue reading “Correlates of Protection”
A Brief history of Immunology
We live in a dangerous world full of a billion pathogens ready to infect us at any time. No wonder nature has endowed us with a strong immunity against these pathogen. The whole history of our knowledge about such an important life story is hardly 120 years. The first Nobel prize in medicine was awardedContinue reading “A Brief history of Immunology”
Dr Ramakanta's Ideas 