Vaccine Efficacy vs Immunological Memory

We have developed Covid vaccines that are highly efficacious ( 94%) as early as December 2020. Yet in the mid 2021, the world reeled under the attack of Delta and the Omicrons. Today we are going to discuss two aspect of the Covid Vaccines: Vaccine Efficacy (VE) Immunological Memory ( IM) Let us classify allContinue reading “Vaccine Efficacy vs Immunological Memory”

Correlates of Protection

In search of a true Correlate of protection against new viruses. The old world of immunology and vaccination are crumbling. For 100 years we thought that our antibody levels are synonymous with Protection against the microbe. Whenever the efficacy of a vaccine needed evaluation, we only measured the serum antibody level against the antigen atContinue reading “Correlates of Protection”

A Brief history of Immunology

We live in a dangerous world full of a billion pathogens ready to infect us at any time. No wonder nature has endowed us with a strong immunity against these pathogen. The whole history of our knowledge about such an important life story is hardly 120 years. The first Nobel prize in medicine was awardedContinue reading “A Brief history of Immunology”

This Virus is Still an Enigma-2

What is happening in Japan, Hong Kong, Singapore and South Korea ? Country Population( in lakh) Total New cases ( on 27.02.22) New cases (per one lakh population) South Korea 513 166,206 323 Singapore 59 16,857 285 Hong Kong 75 17,053 227 Japan 1,258 65,196 52 India 14,024 10,273 0.7 Daily New detection on 27.02.22Continue reading “This Virus is Still an Enigma-2”