As I scanned through the daily covid-19 figures of our zone, I got a pleasant surprise. Even the new Covid-19 cases in the country has fallen below 10,000. Does it mean the present wave has come to an end ? There are too many caveats in this statement. Today Covid-19 has settled down to aContinue reading “Pandemic to Endemic and so on..”
Category Archives: Corona
Everybody likes a Good Pandemic
Year 2019 was devastating for all biotech start ups. Shares of the most established companies dealing with biotech Pharma products had nose dived. Stephan Bancel, the CEO of a little known mRNA company was worried sick. The company’s shares are trading 35% below its initial value. Developing a new drug molecule consumes billions of dollars.Continue reading “Everybody likes a Good Pandemic”
Katalin Kariko
There is hardly any difference between a RNA virus and a mRNA vaccine. Both consist of a strand of RNA surrounded by a lipid envelop. RNA viruses are there for billions of years infecting all forms of life, algae, plants and animals. Thus life has developed astute mechanism of shaking of unwanted RNAs. Every tissueContinue reading “Katalin Kariko”
Merck’s Adenovirus Mis-adventure, 2007
Merck’s Adenovirus Misadventure. Merck is the biggest developer of Vaccines. It is also a pioneer in harnessing Adenoviruses to transfer genetic material into human cells. Today, we have more than a couple of vaccines that uses an adenovirus vector for covid-19 vaccine. But Merck has none. Why ? The story of modern day vaccines beganContinue reading “Merck’s Adenovirus Mis-adventure, 2007”
Vaccine Story-1
Vaccine agents can be either Live whole cell ones, Killed whole cell or sub-unit vaccines. Sub Units can be one specific protein ( Spike protein ) or a slice of DNA or mRNA. Sub unit vaccines are developed only after molecular biology techniques are developed. Between live vaccine and killed vaccine, which is developed earlierContinue reading “Vaccine Story-1”
Dr Ramakanta's Ideas 