Vagus Nerve and Post-biotic



The gut is directly connected to the brain through the *Vagus nerve*, a thick bundle of fibers ( a la Jio fiber connection at your home) that carries more signals upward from the gut than downward from the brain.

Post-biotics:

Chemical compounds created during digestion that behave like neurotransmitters.

Gut Microbes influence the vagal signals by producing *postbiotics*


These include dopamine, serotonin, and GABA, which help regulate emotional stability, mental energy, and stress sensitivity. Postbiotics also influence the behavior of immune cells, which affects inflammation levels throughout the body.
Gut microbes have a lot of say on our parasympathetic system and fight, fright and flight response.

Some species of gut bacteria correlate with increased neuroticism, irritability, and compulsive behavior. Experiments in mice show that altering the microbiome can change mood, social behavior, and even brain structure.

” *ଯଥା ଅନ୍ନ*
      *ତଥା ମନ।*”

This ancient saying from our ଭାଗବତ is spot on the recent medical finding.

“यथा च खाद्यते ह्यन्नं तथा सम्पद्यते मनः ।
यथा च पीयते वारि तथा निर्गद्यते वचः ।।”

ଯଥା ପାଣି, ତଥା ବାଣୀ

People used to accept diseases as the wrath of God and going to temples for cure when Robert Koch in Germany, Louis Pasteur in France, Joseph Lister and John Snow in England introduced the Germ theory.
Soon a new branch of medicine was created ;- Public health.
Pasteur and Koch labs discovered many organisms, vaccine and kochs postulates which culminated in Robert Koch being awarded the Nobel prize in 1905.
Here’s a list –

Casimir Funk, in his 1912 article for the Journal of State Medicine, proposed the existence of at least four vitamins:
one preventing beriberi ( “antiberiberi”); 
one preventing scurvy ( “antiscorbutic”);
one preventing pellagra ( “antipellagric”); and
one preventing rickets ( “antirachitic”).

From there, Funk published a book, The Vitamines, in 1912, and later that year received a Beit Fellowship to continue his research. Soon all the 13 vitamins were discovered in a spate of 10 years. A new science was born Nutrition. Nobel prize of 1929 was awarded for discovery of the first B vitamin.
Here’s a list

It’s now high time that we shall have a new branch of medical science on Microbiata in curing our chronic diseases and dialling down inflammation and auto immune conditions

Published by Dr. Ramakanta

Pediatrician and occasional blogger

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