Pill to Kill disease

Agent, Host and Environment.

Hardly a century ago, we used to go for a change of air for chronic diseases like Tuberculosis or die from simple infections of wounds at home. This has given rise to the era of Sanatoriums and Nursing Homes at hill stations. In Railways we are still issuing Change of air certificate.

Lepers who couldn’t afford this were ostracised to colonies outside the bounds of society. Older people who used to have chronic problems used to leave their environment on their own and go on Banaprastha to forests.

Removal from soil somehow benefited the chronic diseases to certain extent. Psychologically, may be. Let’s call this “the environment therapy.”

Then Alexander Fleming discovered penicillins and that Sanatorium concept changed. More people were treated at home. This is the biggest miracle of the century.

Plague, Polio and Pox were brought to knees. For each microbe, there is a specific drug. Like for each lock there should be a Key.

The concept of disease and cure changed. “Have the disease, Take a pill, kill the agent.” If no relief, add more pills, or change the doctor.

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Today the pill to kill a disease has encroached into the non infectious diseases even. If it’s high Cholesterol, find the limiting enzyme. Switch it off. If it’s BP, shut down the Renin axis. Sugar, BP, Gout all followed suit.

In fact, today a patient taking 10 tablets can explain you the exact 10 biochemical reactions he is switching off in his own system.

Here is the catch.

The number of biochemical reactions that run this human body are roughly one million. All the drugs in our pharmacy can control only 250 of them.

Just calculate: That’s a mere 0.025%. Rest are unknown charter for us. Staggering.

Yet we want to Control all the diseases by tinkering only 0.025% of targets.
That’s ridiculous. Isn’t it ?

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The post Penicillin hypothesis of “have disease, take a pill, kill the culprit” has outlived it’s currency. Time to take care of the soil along with the seed.

For example, Why does breast cancer spread to bones but not to the ovaries or kidneys ?

Although liver and spleen receive blood from every where, why does our liver become the favorite soil for the cancer seeds, not the spleen ?

What mechanism protects our spleen but can not cover the Liver lying just near by ?

How does the matrix protects the organ from the seed to take up ?

It’s time to reinvent our treatment model before we ran out of “One Pill, One disease” concept.